{"id":38355,"date":"2021-06-07T12:06:43","date_gmt":"2021-06-07T12:06:43","guid":{"rendered":"https:\/\/matis.is\/?p=38355"},"modified":"2021-06-07T12:06:44","modified_gmt":"2021-06-07T12:06:44","slug":"state-of-the-art-in-benefit-risk-analysis-medicine","status":"publish","type":"post","link":"https:\/\/matis.is\/en\/greinar\/state-of-the-art-in-benefit-risk-analysis-medicine\/","title":{"rendered":"State of the Art in Benefit-Risk Analysis: Medicine"},"content":{"rendered":"<p id=\"sp010\">Benefit \u2013 risk assessment in medicine has been a valuable tool in the regulation of medicines since the 1960s. Benefit risk assessment takes place in multiple stages during a medicine&#039;s life-cycle and can be conducted in a variety of ways, using methods ranging from qualitative to quantitative. Each benefit \u2013 risk assessment method is subject to its own specific strengths and limitations. Despite its widespread and long-time use, benefit \u2013 risk assessment in medicine is subject to debate and suffers from a number of limitations and is currently still under development.<\/p>\n\n\n\n<p id=\"sp015\">This state of the art review paper will discuss the various aspects and approaches to benefit \u2013 risk assessment in medicine in a chronological pathway. The review will discuss all types of benefit \u2013 risk assessment a medicinal product will undergo during its lifecycle, from Phase I clinical trials to post-marketing surveillance and health technology assessment for inclusion in public formularies. The benefit \u2013 risk profile of a drug is dynamic and differs for different indications and patient groups. At the end of this review we conclude benefit \u2013 risk analysis in medicine is a developed practice that is subject to continuous improvement and modernization. Improvement not only in methodology, but also in cooperation between organizations can improve benefit \u2013 risk assessment.<\/p>\n\n\n\n<p><strong><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0278691511002523\">Link to article<\/a><\/strong><\/p>","protected":false},"excerpt":{"rendered":"<p>Benefit\u2013risk assessment in medicine has been a valuable tool in the regulation of medicines since the 1960s. Benefit\u2013risk assessment takes [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"template-greinar.php","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[2011],"tags":[],"class_list":["post-38355","post","type-post","status-publish","format-standard","hentry","category-greinar"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>State of the Art in Benefit-Risk Analysis: Medicine - Mat\u00eds<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/matis.is\/en\/greinar\/state-of-the-art-in-benefit-risk-analysis-medicine\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"State of the Art in Benefit-Risk Analysis: Medicine - Mat\u00eds\" \/>\n<meta property=\"og:description\" content=\"Benefit\u2013risk assessment in medicine has been a valuable tool in the regulation of medicines since the 1960s. 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