Ritrýndar greinar

The alternative complex III from Rhodothermus marinus – a prototype of a new family of quinol: electron acceptor oxidoreductases

Höfundar: Manuela M. Pereira, Patricia N. Refojo, Gudmundur O. Hreggvidsson, Sigridur Hjorleifsdottir and Miguel Teixeira

Útgáfa: FEBS Letters

Útgáfuár: 2007


The biochemical and genetic search for a bc 1 complex in Rhodothermus marinus was always fruitless; however, a functional equivalent, i.e. having quinol:cytochrome c oxidoreductase activity was characterized. Now, with the sequencing of R. marinus genome, it was possible to assign the N-terminal sequences of several proteins of this complex to its coding genes. The alternative complex III from R. marinus has the same genomic organization of the so-called MFIcc complexes, proposed to be oxidoreductases of the respiratory and photosynthetic electron transfer chains. In this report, we establish undoubtedly the existence of an alternative complex III, a functional substitute of the bc 1 complex, by its identification at both the biochemical and genomic level.

Hlekkur að grein