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Are you interested in participating in a study? Effects of cystic fibrosis on inflammatory factors

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Biotechnology

Matís and the Laboratory of Geriatrics, Landakoti 5L, are requesting participants in a study that has been approved by the Science Ethics Committee.

Participants must be adults, 40 years and older with a body mass index (BMI) ≥ 27 kg / m2(see table with calculated body mass index below) and waist circumference ≥ 88cm in women and ≥ 102 cm in men. Participants who exercise more than 30 min / day are excluded from participation as well as pregnant women or women who are breastfeeding. Individuals who are in contact and interested in participating in the study should reduce their consumption of omega-3-containing foods and avoid fish oil for 2 weeks before and during the intervention.

  • The aim of the study is to investigate the effects of cystic fibrosis on inflammatory factors in obese adults, as well as to investigate whether cystic fibrosis affects other physiological variables (blood sugar and blood lipids).
  • Participants will be randomly divided into two groups that receive either:
    a)  Seaweed powder (3 capsules = 1200 mg / day) for 10 weeks  b) Placebo powder (3 capsules / day) for 10 weeks.
  • Participation in the study involves attending at the beginning and end of the period for body measurements and biopsies, as well as answering a general questionnaire about diet and health at the beginning of the study. Measurements of body composition, waist circumference, height and weight will be performed. The main measurements in the blood are inflammatory factors, blood sugar and lipids in the blood.
  • Balloon seaweed (Fucus vesiculosus) is rich in iodine, indigestible starch, salt and bioactive substances. Seaweed powder is formed when certain bioactive substances are extracted from the bladder seaweed and isolated. These bioactive ingredients are placed in gelatin capsules for easy ingestion. The use of bladder seaweed for human consumption is known and research on bioactive substances in bladder seaweed suggests that bladder seaweed powder may have a positive effect on physiological parameters (inflammatory factors and blood sugar).
  • Participation is not paid for.

Interested parties who meet the above criteria are asked to have
contact Aníta Sif Elídóttir at 844-7131 or send an e-mail to anitas@landspitali.is


The person responsible for the study is Alfons Ramel, Professor at the Faculty of Food and Nutrition, University of Iceland (alfonsra@hi.isphone: 543-9875).  Aníta Sif Elídóttir is a nutritionist and an employee of the Faculty of Food and Nutrition at the University of Iceland and assists in the implementation of the research.

Table 1 - Minimum weight required to meet body mass index requirements ≥ 27 kg / m2

Height (m)Weight (kg)
1,6069
1,6271
1,6473
1,6674
1,6876
1,7078
1,7280
1,7482
1,7684
1,7886
1,8087
1,8289
1,8491
1,8693
1,8895
1,9097
1,92100
1,94102
1,96104
1,98106
2,00108

Body mass index is calculated from height and weight according to the formula weight / height2 (kg / m2).

Those who contact the researchers are only expressing an interest in further information and do not undertake to participate.

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