Peer-reviewed articles

Complete genome sequence of Streptomyces lividans TK24

Authors: Rückert C., Albersmeier A., Busche T., Jaenicke S., Winkler, A, Friðjónsson OH, Hreggviðsson G.Ó., Lambert, C, Badcock D, Bernaerts K, Anne J., Economou A., Kalinowski J.

Version: Journal of Biotechnology

Publication year: 2015


Streptomyces lividans TK24 is the standard host for the heterologous expression of a number of different proteins and antibiotic-synthesizing enzymes. As such, it is often used as an experimental microbial cell factory for the production of secreted heterologous proteins including human cytokines and industrial enzymes, and of several antibiotics. It accepts methylated DNA and is an ideal Streptomyces cloning system. Here, we report the complete genome sequence of S. lividans TK24 that includes a plasmid-less genome of 8,345 Mbp (72,24% G + C content).

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