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Bubble seaweed extract (Fucus vesiculosus) has been extensively studied and the bioactive properties of the extract have been demonstrated in in vitro research on human skin cells. The aim of the study described in this report was to investigate the effect of a lotion containing bioactive substances from bubble seaweed on human skin. in vivo.
A double-blind intervention study was conducted, with two comparable groups of people between the ages of 40 and 60, who used either a lotion containing the bioactive seaweed extract or a cream containing all the same ingredients except the extract (control). The effects of the creams on skin properties were measured three times over a twelve week period. The first measurement was performed at the beginning (before the use of the cream started), then after six weeks of daily use (morning and evening) of the cream and at the end of the intervention after 12 weeks. The skin of the participants was measured with the Dermalab Series Clinique Combo from Cortex technology, which collected data on, among other things, skin elasticity, moisture and collagen strength.
Skin elasticity increased over time in both groups. The increase was more pronounced in the group that used the cream with bubble seaweed extract. Two parameters were measured by ultrasonic skin imaging: collagen concentration and skin thickness. Collagen concentrations did not increase in the participants' skin during the study, and no detectable differences were found in the participants' skin thickness over time. However, the skin was thicker in the group that used the cream with bubble seaweed extract than the control group in the third measurement. Moisture in the participants' skin increased between the first and second measurement, but decreased again slightly from the second to the third measurement. The results showed that the use of the creams increases the moisture in the skin, but other factors also have an effect, such as the humidity in the atmosphere. The skin moisture of the group using the bubble seaweed extract cream tended to be higher compared to the control group at the third measurement.
The conclusion of the study is that the lotion that contained the extract of bubble seaweed had a positive effect on the skin of the participants. However, the results were also positive in the group using the control cream, and often the difference between the two groups was not significant. In cases where the difference between the groups was significant, it was in favor of the bubble seaweed cream.
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Fucus vesiculosus extract has been extensively studied, and has shown to possess remarkable bioactive properties on human skin cells in vitro. The aim of this work was to study the effects of skin cream containing the bioactive seaweed Fucus vesiculosus extract on human skin in vivo.
This was done via double blind intervention study, with two comparable groups of people in the age range 40 to 60, who used either a skin cream containing the bioactive seaweed extract, or a cream containing all the same ingredients aside from the extract (control) , or a placebo. The effects of the creams on skin parameters were measured three times over a period of twelve weeks. The skin of the participants was measured with a Dermalab Series Clinique Combo from Cortex technology, which gathered data about eg skin elasticity, hydration, and collagen intensity, at baseline, after six weeks and 12 weeks of daily use (mornings and evenings) of the cream.
Elasticity increased over time for both groups. The increase was more noticeable in the group using the cream with the Fucus vesiculosus extract. Two parameters were measured using ultrasonic skin imaging: collagen intensity and skin thickness. The collagen intensity did not increase in the skin of the participants during the study and no differences in thickness of the skin of the participants were seen over time. However, the skin was thicker for the group using the cream with the Fucus vesiculosus extract than the placebo group in the third measurement. The hydration increased in the skin of the participants from the first to the second measurement but decreased again slightly from the second to third measurement. It can be concluded that using the creams increases hydration in the skin but other factors have an impact too, such as the hydration level in the atmosphere. A trend was seen for more hydration in the group using the cream with the Fucus vesiculosus extract compared to the placebo group in the third measurement.
In conclusion, the skin cream containing the bioactive seaweed extract had a positive impact on the skin of the participants. However, the group using the placebo cream also experienced positive results, and often the differences between the two groups were not significant. When significant differences were observed, they favored the bioactive cream.